XTEM BioLab
Structure Really Matters
Many scientists have been trying to find the protein structure for scientific or commercial reasons in the belief that "Structure determines function".
However, preparation of specimens itself has been a big obstacle. We promise that structural scientists could save their priceless time and efforts by using our experimental equipments.
XTEM BioLab
Paradigm Shift in Methodology
A lot of efforts has been made to find out protein structure. X-ray crystallography has been good tools but now cryo-EM will be a superior tool to dissolve protein structure.
But likewise X-ray crystallography, cryo-EM also had difficulties getting good grids. Not only do we solve the problems by improving convetional method, but also we propose new ways to get good grids.
Diffracto Pluger and Micro Spray Machine will be the answer preparing the specimens in cryo-EM Fields.
ABOUT
Our Mission
Founded to support structural scientists
Save your priceless time & efforts
In biology there is no famous saying that structure determines function. In other words, knowing the structure will also help us estimate the function of protein and develop new drugs as a result.
Scientists have made an effort to figure out the protein structure. As a result of their efforts, X-ray crystallography appeared. But X-ray crystallography is challenging in membrane proteins and large protein complexes whose crystals are barely obtainable.
Technical breakthrough brought the cryo-EM, which has almost been a concept, bring into the real world. But we needs more breakthroughs in preparing vitrified specimens. Conventioal method uses paper filtering. But this method can hardly guarantee the quality of specimen. So a lot of researchers have spent most of the research time and effort to make good grids.
We came up with the idea that we could estimate the thickness of the remaining samples in the grid if we were to measure the change of the intensity of a diffracton spot.
We embodied above idea into experimental instruments, Diffracto Plunger.
We have a firm belif that our instruments save priceless time and efforts wasted.
Use our instrument and save your time and efforts.
Good luck.
Profiles
CTO : Nam-Chul Ha, Ph.D.
Professor
CTO of XTEM BioLab CO., Ltd.
Seoul National University,
College of Agriculture and Life Sciences,
Department of Agricultural Biotechnology,
Program in Food Science and Biotechnology
Food Biochemistry Lab
e hanc210@gmail.com
t +82-10-3908-0984
Education and Training
1991-1997 B.S. in Microbiology, Seoul National University
1997-2002 Ph.D. in Biology, POSTECH
Professional Career
2002-2004 Post-Doc., Stanford University
2004-2008 Assistant Professor, Pusan National University
2008-2013 Associate Professor, Pusan National University
2013-2014 Professor, Pusan National University
2014-2016 Associate Professor, Seoul National University
2016-Present Professor, Seoul National University
2019 – Present XTEMBIOLAB Co. , SEOUL, KOREA
Chief Technology Officer
CEO : Youngjoo Na, ex CFA, FRM
CEO of XTEM BioLab CO., Ltd.
e nyj9109@gmail.com
t +82-10-2027-7390
Education and Training
1991-1997 B.S. in Microbiology, Seoul National University
1998-2000 M.B.A. degree in Business Administration, Seoul National University
Work Experiences
2000–2000 Korea Housing Bank, SEOUL, KOREA
2000–2003 Hyundai Investment & Securities Co. , SEOUL, KOREA
2003–2006 Hangaram Investment Management Co. , SEOUL, KOREA
2006–2010 LK Asset Management Co. , SEOUL, KOREA
2019 – Present XTEMBIOLAB Co. , SEOUL, KOREA
Chief Executive Officer
SOLUTIONS
Our Products
Diffracto Plunger & Micro Spray Machine
We recommand this solution if you want to make good grids. Our machine is based on the scientific reasoning not on the trial and error as was conventional method.
Until recently structural scientists have no choice but to take trial and error strategy in preparing cryo-EM grids. But we believe the situation is in a different phase by our machine, Diffracto Plunger & Micro Spray Machine.
There are 5 big challenges in preparing good cryo-EM grids.
1)Air-water interface
2)Surface tension
3)The vibrational motions of the proteins
4)Grid properties, Glow discharging
5)Protein itself as an impotance infuluencer governing the ice thickness.
Our machine almost solves the 5 big challenges. It is based on the simple scientific rule that the diffraction shows the average or comprehensive status of 2 levels of 2D-regularity in quantifoil grids. If we examine the intensity change of the diffraction spots by blotting with filter papers, we not only could monitor the grid state in real time but obtain the right time for plunge-freezing for reasonable ice thickness. This could result in reduction of the number of grids, which should be examined in cryo-EM machines.
We provide 3 modes in preparing cryo-EM grids and the researchers could have a choice.
Our machine reduce your priceless time and effort.
Good luck.
Nylon-mesh-based sample holders for fixed target femtosecond crystallography by Dr. Nam, Ki-Hyun is now preparing
We want to add this invention to our solutions if there is chance and allowance from Dr. Nam, Ki-Hyun.
BOARD
| no | category | title | name | date | view |
|---|---|---|---|---|---|
| category | Frequently asked question about this pages and delevery process while ordered post didn't arrive 7 | admin | now | 50 | |
| 9 | category | Good design.I will be glad if you see my latest work. | Jack | 5 hour ago | 175 |
| 8 | category | awesome work..really very inspirational job.congrats | David James | 3 days ago | 534 |
| 7 | category | Beautiful design and layout.. Great job | BaByliss | dev 22 | 51 |
| 6 | category | Amazing work one really feels like in a stone age. Impressive! | Oliver Warren | dev 7 | 235 |
| 5 | category | Unbelievable divat not dive project itself is awesome but it's presentation here... congratulations! | DIANA | nov 31 | 165 |
| 4 | category | Excellent work! Great presentation! | Jett | nov 18 | 25 |
| 3 | category | od design.I will be glad if you see my latest work. | Lincoln | nov 17 | 266 |
| 2 | category | Beautiful design and layout.. Great job | Blaise | nov 13 | 369 |
| 1 | category | Amazing work one really feels like in a stone age. Impressive! | Raphael | nov 4 | 16 |
CONTACT US
Location
XTEM Biolab Co., Ltd.
Room 590 5th Floor, 4, Gukhoe-daero 72-gil, Yeongdeungpo-gu, Seoul, Republic of Korea(07238)
Contact
t. +82-10-2027-7390
e. nyj9109@gmail.com